In the past decade, over 1 million people have been killed and over 5 million have been seriously injured or permanently disabled because of road crashes in India. Despite the scale of the problem, there are limited case- studies of structured, evidence-based interventions to reduce the loss of life and limb on Indian roads. The Zero Fatality Corridor (ZFC) initiative was conceived in this context, with a vision to build a replicable and scalable model to reduce road crash deaths in India. In 2016, SaveLIFE Foundation and Mahindra & Mahindra Ltd. partnered with the Government of Maharashtra to reduce road crash deaths on the Yashwantrao Chavan Mumbai-Pune Expressway to from an annual average of 135 to 0 (zero) by the year 2021 - transforming it into India's first Zero Fatality Corridor.